R&S Chemicals


Ramesh C. Gupta, PhD

Education : M.Sc. & Ph.D. Himachal Pradesh University (1978, Simla, India).

Industrial and academic Experience: More than 20 years of industrial experience. Worked as a Senior Demonstrator at the University of Liverpool (1979-81). From 1981-1985, worked as a post-doctoral fellow at the University of Newcastle-Upon-Tyne.

Publications Published 31 papers in peer-reviewed journals, and five U.S. patents.

Professional Expertise More than 25 years of industrial experience. Expert in chemical synthesis, process development, and in the improvement of known synthetic methods, especially with regard to yield. Worked on the process development on a large number of medicinal compounds such as acyclovir (antiviral), astemizole (antihistamine), chloroprocaine hydrochloride (local anesthetic), ephedrine and Y-ephedrine (decongestant), felbamate (antiepileptic), gemfibrozil (to lower cholesterol and triglyceride), ketoconazole (oral antifungal), nadolol (antihypertensive and antianginal), pyridoglutethimide (aromatase inhibitor in postmenopausal breast cancer patients), tolrestat (for the treatment of diabetic neuropathy) and a number of anticancer drugs such as daunorubicine, docetaxel, doxorubicine, orataxel, paclitaxel, and PALA disodium. Also, expertise in several synthetic areas, including synthesis of anthracyclines, flavonoids, polyamines, polypeptides, polyphenols, taxoids, triazines and triazinone derivatives.